Sildenafil is actually a powerful and selective inhibitor of cGMP-unique phosphodiesterase style 5 (PDE5), and that is chargeable for degradation of cGMP inside the corpus cavernosum. The molecular framework of sildenafil is similar to that of cGMP and acts for a aggressive binding agent of PDE5 in the corpus cavernosum, resulting in additional cGM… Read More